Description

n-Boc-4-(4-Carboxyphenyl) Piperidine is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemists and process development scientists seeking to construct complex molecular architectures with precision. It is primarily utilized in the research and development of novel active pharmaceutical ingredients (APIs), particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates targeting various therapeutic areas.
• Peptidomimetic Chemistry: Used in the design and construction of peptide-like molecules to enhance stability and bioavailability.
• Ligand and Receptor Probe Development: Serves as a core scaffold for creating chemical probes in biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.
• Academic and Industrial R&D: Employed in discovery chemistry programs for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	n-Boc-4-(4-Carboxyphenyl) Piperidine
CAS No.	149353-75-3
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	1-Boc-4-(4-Carboxyphenyl)piperidine; tert-Butyl 4-(4-carboxyphenyl)piperidine-1-carboxylate; 4-(4-Carboxyphenyl)piperidine-1-carboxylic acid tert-butyl ester; 4-(1-Boc-4-piperidyl)benzoic acid; 4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid; 4-Piperidinecarboxylic acid, 4-(4-carboxyphenyl)-, 1-(1,1-dimethylethyl) ester; BOC-Pip(4-Ph-COOH)
EINECS	Contact for details

Quality Control

Our n-Boc-4-(4-Carboxyphenyl) Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring material for research, development, and pre-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.