Description

4-[(2,4-Difluorophenoxy)Methyl]Benzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its difluorophenoxy moiety can impart desirable metabolic stability and bioavailability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers and charge-transport materials used in display technologies and organic electronics.
• Polymer Modification: Incorporated into polymer backbones to create specialty polyesters or polyamides with enhanced chemical resistance and thermal properties.
• Chemical Research & Development: A versatile reagent for constructing complex molecular architectures in academic and industrial R&D laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-[(2,4-Difluorophenoxy)Methyl]Benzoic Acid
CAS No.	149288-45-9
Molecular Formula	C14H10F2O3
Molecular Weight	264.23 g/mol
Synonyms	4-[(2,4-Difluorophenoxy)methyl]benzoic acid; Benzoic acid, 4-[(2,4-difluorophenoxy)methyl]-; 2,4-Difluorophenyl 4-carboxybenzyl ether; 4-(2,4-Difluorophenoxymethyl)benzoic acid; p-[(2,4-Difluorophenoxy)methyl]benzoic acid; 4-Carboxybenzyl 2,4-difluorophenyl ether; (4-Carboxybenzyloxy)-2,4-difluorobenzene
EINECS	Contact for details

Quality Control

Our 4-[(2,4-Difluorophenoxy)Methyl]Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.