Description

tert-Butyl 2-(4-Cyanobenzyl)Hydrazinecarboxylate is a high-purity, protected hydrazine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a cyano group and a Boc-protected hydrazine, makes it an invaluable reagent for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the hydrazine moiety contributes to biological activity.
• Heterocyclic Chemistry: Essential for constructing pyrazole, triazole, and other nitrogen-based heterocyclic scaffolds prevalent in medicinal and material chemistry.
• Peptidomimetics & Bio-conjugation: Employed in the design of peptide analogs and for introducing functional handles into biomolecules via its reactive hydrazine group.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	tert-Butyl 2-(4-Cyanobenzyl)Hydrazinecarboxylate
CAS No.	149267-90-3
Molecular Formula	C₁₃H₁₇N₃O₂
Molecular Weight	247.29 g/mol
Synonyms	1-Boc-2-(4-cyanobenzyl)hydrazine; tert-Butyl (4-cyanobenzyl)carbazate; N-(tert-Butoxycarbonyl)-N'-(4-cyanobenzyl)hydrazine; Carbamic acid, N-[(4-cyanophenyl)methyl]-, 1,1-dimethylethyl ester; Boc-NH-NH-CH2-(4-CN-Ph); (4-Cyanobenzyl)hydrazine, N-Boc protected; tert-Butyl N-[(4-cyanophenyl)methyl]hydrazinecarboxylate
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 2-(4-Cyanobenzyl)Hydrazinecarboxylate adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical applications, ensuring reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.