Description

2-[2-(Trifluoromethyl)Phenoxy]Tetrahydro-2H-Pyrane is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethylphenoxy ether structure. This compound is valued for its role in modulating the physicochemical properties of target molecules, particularly in enhancing metabolic stability and lipophilicity. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the trifluoromethyl group for improved bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of specialty chemicals for electronic displays and organic light-emitting diodes.
• Organic Synthesis & Catalysis: Employed as a protected phenol derivative or a specialized ligand in complex organic transformations and catalytic cycles.
• Material Science Research: Used in academic and industrial R&D for creating polymers and advanced materials with specific thermal or chemical resistance properties.

Basic Information

Product Name	2-[2-(Trifluoromethyl)Phenoxy]Tetrahydro-2H-Pyrane
CAS No.	149209-47-2
Molecular Formula	C12H13F3O2
Molecular Weight	246.23 g/mol
Synonyms	2-(2-(Trifluoromethyl)phenoxy)tetrahydro-2H-pyran; 2H-Pyran, tetrahydro-2-[2-(trifluoromethyl)phenoxy]-; 2-(α,α,α-Trifluoro-o-tolyloxy)tetrahydropyran; THP ether of 2-(Trifluoromethyl)phenol; 2-(2-Trifluoromethylphenoxy)tetrahydropyran; o-Trifluoromethylphenyl tetrahydropyran-2-yl ether
EINECS	Contact for details

Quality Control

Our 2-[2-(Trifluoromethyl)Phenoxy]Tetrahydro-2H-Pyrane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.