Description

4,6-Difluoro-Indan-1-Ylamine Hydrochloride is a high-purity, fluorinated indane derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for synthesizing fluorinated organic compounds with unique electronic and photophysical properties.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and diagnostic agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4,6-Difluoro-Indan-1-Ylamine Hydrochloride
CAS No.	148960-40-1
Molecular Formula	C9H10ClF2N
Molecular Weight	205.63 g/mol
Synonyms	1-Amino-4,6-difluoroindane hydrochloride; 4,6-Difluoro-1-indanamine hydrochloride; 4,6-Difluoroindan-1-amine HCl; (4,6-Difluoro-2,3-dihydro-1H-inden-1-yl)amine hydrochloride; 1-Indanamine, 4,6-difluoro-, hydrochloride; 4,6-Difluoro-1-aminoindane hydrochloride
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-Indan-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.