Description

4-Fluoro-Indan-1-Ylamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key chiral precursor for synthesizing complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of central nervous system (CNS) active drugs, enzyme inhibitors, and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex indane-based molecular frameworks in academic and industrial R&D labs.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-Fluoro-Indan-1-Ylamine Hydrochloride
CAS No.	148960-34-3
Molecular Formula	C9H11FN • HCl
Molecular Weight	187.65 g/mol (Free base: 151.19 g/mol)
Synonyms	1-Amino-4-fluoroindane hydrochloride; (4-Fluoro-1-indanyl)amine hydrochloride; 4-Fluoroindan-1-amine HCl; 4-Fluoro-1-indanamine hydrochloride; 1-Indanamine, 4-fluoro-, hydrochloride; 4-Fluoro-1-aminoindane HCl; (RS)-4-Fluoroindan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-Indan-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.