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B-Galcer, B-Galactosylceramide CAS NO 148439-48-9


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CAS No.:148439-48-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

B-Galcer, B-Galactosylceramide is a bioactive sphingolipid, a critical component of cell membranes and a key signaling molecule in immunological and neurological processes. Its high purity and defined structure make it an essential standard and reagent for advanced life science research and pharmaceutical development. This compound is primarily utilized by researchers and manufacturers in the fields of immunology, neuroscience, and drug discovery, where precise molecular tools are required to study lipid rafts, cellular signaling pathways, and autoimmune responses.

Application

  • Immunological Research: Used as a potent antigen for invariant Natural Killer T (iNKT) cells to study immune modulation, autoimmune diseases, and vaccine adjuvants.
  • Neuroscience Studies: Serves as a key component in researching myelin sheath formation, neuronal development, and the pathology of diseases like multiple sclerosis.
  • Pharmaceutical Reference Standard: Acts as a certified reference material (CRM) for quality control and assay development in drug manufacturing targeting lipid-mediated pathways.
  • Biochemical Reagent: Employed in in vitro assays to investigate cell membrane dynamics, lipid-protein interactions, and sphingolipid metabolism.
  • Drug Discovery & Development: Utilized in high-throughput screening (HTS) to identify novel therapeutic agents that modulate iNKT cell activity.

Basic Information

Product Name B-Galcer, B-Galactosylceramide
CAS No. 148439-48-9
Molecular Formula C48H93NO8
Molecular Weight 812.26 g/mol
Synonyms α-Galactosylceramide; α-GalCer; KRN7000; AGL-1075; Galactosyl Ceramide; GalCer; β-D-Galactosyl-N-acylsphingosine; N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]tetracosanamide 6-O-β-D-galactopyranoside
EINECS Contact for details

Quality Control

Our B-Galactosylceramide is produced under stringent quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality protocols are designed to meet the exacting requirements of pharmaceutical reference material and biochemical reagent applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability and purity. Allow the vial to warm to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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