Description

Gdp-L-Fuc.2Na is a high-purity nucleotide sugar derivative, specifically the disodium salt of Guanosine diphosphate L-fucose. This compound serves as a critical activated donor substrate for fucosyltransferase enzymes in biochemical synthesis. It is essential for researchers and manufacturers in the life sciences, particularly for studying and producing glycoproteins, glycolipids, and complex carbohydrates. Its reliable quality ensures consistent results in enzymatic synthesis and glycosylation research.

Application

• Enzymatic Glycosylation: As a key substrate for in vitro fucosylation reactions catalyzed by fucosyltransferases.
• Glycobiology Research: For studying fucose-related biological processes, including cell signaling, immune response, and pathogen recognition.
• Bioconjugate & Vaccine Development: In the synthesis of well-defined glycoconjugates for therapeutic and diagnostic applications.
• Pharmaceutical Intermediates: Used in the development and production of novel glycoprotein-based drugs.
• Diagnostic Reagent Manufacturing: As a component in kits for detecting specific glycosylation patterns or enzyme activity.
• Biocatalyst & Enzyme Characterization: For assaying the activity and specificity of fucosyltransferases.

Basic Information

Product Name	Gdp-L-Fuc.2Na
CAS No.	148296-47-3
Molecular Formula	C16H23N5O15P2Na2
Molecular Weight	673.30 g/mol (anhydrous basis)
Synonyms	Guanosine 5'-(trihydrogen diphosphate) P'-(6-deoxy-α-L-galactopyranosyl) ester, disodium salt; GDP-L-fucose disodium salt; Guanosine diphosphate L-fucose disodium; GDP-α-L-fucose Na2; 6-Deoxy-α-L-galactopyranosyl guanosine diphosphate disodium salt; Activated L-fucose donor; Fucosyl donor substrate.
EINECS	Contact for details

Quality Control

Every batch of Gdp-L-Fuc.2Na is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and bioprocessing. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation, and moisture content. Our quality commitment supports applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg
Biological Activity	Conforms (Enzymatic Assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.