Description

Gdp-D-Mannose Disodium Salt is a high-purity biochemical reagent and nucleotide sugar derivative essential for glycosylation research and enzymatic synthesis. This compound serves as a critical activated mannose donor, enabling the study and production of complex carbohydrates and glycoconjugates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in glycobiology, drug development, and the synthesis of oligosaccharides.

Application

• Glycobiology Research: As a key substrate for studying glycosyltransferase enzymes and glycosylation pathways.
• Enzymatic Synthesis: Serves as an activated sugar donor for the in vitro enzymatic production of mannose-containing oligosaccharides and glycans.
• Pharmaceutical Development: Used in the research and development of glycoprotein-based therapeutics, vaccines, and diagnostic agents.
• Biochemical Assays: Acts as a standard or reagent in high-throughput screening assays for enzyme activity and inhibitor discovery.
• Carbohydrate Chemistry: A building block for the chemoenzymatic synthesis of complex carbohydrate structures and probes.
• Cell Culture & Media Supplement: Potential application in specialized cell culture media to study cellular glycosylation processes.

Basic Information

Product Name	Gdp-D-Mannose Disodium Salt
CAS No.	148296-46-2
Molecular Formula	C16H23N5Na2O16P2
Molecular Weight	649.29 g/mol
Synonyms	GDP-D-Mannose disodium salt; Guanosine 5'-(trihydrogen diphosphate) P'→5'-ester with D-mannose, disodium salt; GDP-α-D-mannose disodium; GDP-Man disodium salt; β-GDP-mannose disodium salt; Mannose-1-phosphate guanylyltransferase substrate; GUANOSINE-5'-DIPHOSPHO-MANNOSE DISODIUM SALT
EINECS	Contact for details

Quality Control

Our Gdp-D-Mannose Disodium Salt is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is analyzed with advanced techniques including HPLC and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (5% solution)	6.0 - 8.0
Endotoxin	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.