Description

2-Chloro-4-Fluoro-5-Iodophenol is a halogenated phenol derivative serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its multi-halogenated structure makes it a critical building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core for bioactivity.
• Liquid Crystal Materials: Serves as a building block for halogenated biphenyl and terphenyl cores used in electronic display technologies.
• Organic Synthesis & Research: A valuable reagent for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to introduce the phenol-iodo functional group.
• Material Science: Employed in the synthesis of advanced polymers and functional materials requiring halogenated phenolic units.
• Dye and Pigment Intermediate: Used in the production of specialized halogenated dyes and colorants.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Iodophenol
CAS No.	148254-33-5
Molecular Formula	C6H3ClFIO
Molecular Weight	287.44 g/mol
Synonyms	5-Iodo-2-chloro-4-fluorophenol; 2-Chloro-4-fluoro-5-iodo-1-hydroxybenzene; Phenol, 2-chloro-4-fluoro-5-iodo-; 4-Fluoro-2-chloro-5-iodophenol; 2-Chloro-4-fluoro-5-iodophenol; 5-Iodo-4-fluoro-2-chlorophenol; 148254-33-5; 2-Chloro-4-fluoro-5-iodo phenol
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-5-Iodophenol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.