Description

4-Chloroquinoline-6-Carboxylic Acid Ethyl Ester is a high-purity, versatile quinoline-based building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its specific chloroquinoline scaffold is highly valued. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for creating organic ligands, dyes, and photoactive compounds used in advanced materials.
• Chemical Synthesis: Employed in medicinal and combinatorial chemistry for structure-activity relationship (SAR) studies and library generation.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological development and exploratory synthesis.

Basic Information

Product Name	4-Chloroquinoline-6-Carboxylic Acid Ethyl Ester
CAS No.	148018-34-2
Molecular Formula	C₁₂H₁₀ClNO₂
Molecular Weight	235.67 g/mol
Synonyms	Ethyl 4-Chloroquinoline-6-carboxylate; 6-Carbethoxy-4-chloroquinoline; 4-Chloro-6-quinolinecarboxylic Acid Ethyl Ester; Ethyl 4-Chloro-6-quinolinecarboxylate; 4-Chloro-6-(ethoxycarbonyl)quinoline; Quinoline-6-carboxylic acid, 4-chloro-, ethyl ester; 148018-34-2; 4-Chloroquinoline-6-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloroquinoline-6-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.