Description

4-Chloro-6-Hydroxyquinoline is a versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated hydroxyquinoline structure makes it a valuable intermediate for developing compounds with specific biological and chemical activities. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its quinoline core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, dyes, and fluorescent markers due to the quinoline scaffold's photophysical properties.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Chloro-6-Hydroxyquinoline
CAS No.	148018-29-5
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	6-Hydroxy-4-chloroquinoline; 4-Chloro-6-quinolinol; 4-Chloro-6-hydroxy-quinoline; Quinoline, 4-chloro-6-hydroxy-; 4-Cl-6-OH-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Hydroxyquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP standards where applicable, ensuring the material is suitable for demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.