Description

Quinazoline, 4,7-Dichloro-2-(Trifluoromethyl)- is a high-purity, halogenated quinazoline derivative serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesis and screening programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinazoline core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries for high-throughput screening (HTS).
• Material Science: Investigated for use in the synthesis of organic electronic materials and advanced polymers.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for medicinal chemistry and discovery chemistry projects.

Basic Information

Product Name	Quinazoline, 4,7-Dichloro-2-(Trifluoromethyl)-
CAS No.	147972-25-6
Molecular Formula	C9H3Cl2F3N2
Molecular Weight	267.04 g/mol
Synonyms	4,7-Dichloro-2-(trifluoromethyl)quinazoline; 2-(Trifluoromethyl)-4,7-dichloroquinazoline; 4,7-Dichloro-2-trifluoromethylquinazoline; Quinazoline, 4,7-dichloro-2-(trifluoromethyl)-; 147972-25-6; 4,7-Dichloro-2-(trifluoromethyl)quinazoline
EINECS	Contact for details

Quality Control

Our Quinazoline, 4,7-Dichloro-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.