Description

4-o-(2-Amino-2-Deoxy-α-Glucopyranosyl)-3-Deoxy-Manno-2-Octulosonic Acid is a complex, high-purity carbohydrate derivative and a key structural component of bacterial lipopolysaccharides. This compound is critical for advanced biochemical research and the development of novel therapeutic agents and diagnostic tools. It is primarily utilized by research institutions and pharmaceutical companies specializing in glycobiology, immunology, and antibacterial drug discovery.

Application

• Biochemical Research: As a reference standard and substrate for studying bacterial endotoxin structure and biosynthesis pathways.
• Glycoconjugate Synthesis: A crucial building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycoconjugates.
• Vaccine Development: Used in research for designing conjugate vaccines targeting Gram-negative bacterial infections.
• Enzyme Assay Substrate: Serves as a specific substrate for enzymes involved in lipopolysaccharide (LPS) assembly, such as glycosyltransferases.
• Immunology Studies: Employed to investigate host-pathogen interactions and the innate immune response to bacterial endotoxins.
• Analytical Standard: Essential for the calibration and validation of analytical methods (HPLC, MS) used in carbohydrate and pharmaceutical analysis.

Basic Information

Item	Details
Product Name	4-o-(2-Amino-2-Deoxy-α-Glucopyranosyl)-3-Deoxy-Manno-2-Octulosonic Acid
CAS No.	147769-42-4
Molecular Formula	C14H24NO12
Molecular Weight	398.34 g/mol
Synonyms	KDO-GlcN; 3-Deoxy-D-manno-oct-2-ulosonic acid-(2→4)-2-amino-2-deoxy-α-D-glucopyranoside; α-KDO-(2→4)-α-D-GlcN; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-3-deoxy-D-manno-oct-2-ulosonic acid; LPS Core Structure Derivative; Bacterial Core Oligosaccharide Fragment; Glycosyl KDO Derivative
EINECS	Contact for details

Quality Control

Every batch of 4-o-(2-Amino-2-Deoxy-α-Glucopyranosyl)-3-Deoxy-Manno-2-Octulosonic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.