Description

8-Oxabicyclo[3.2.1]Oct-6-En-3-One,2-(1-Methylethyl)-,(1R,2S,5R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactone compound, serving as a critical chiral building block in advanced organic synthesis. Its rigid, oxygen-containing fused ring structure makes it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in antiviral, anti-inflammatory, or central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity.
• Fine Chemical Production: Serves as a versatile precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring complex, oxygenated ring systems.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Material Science: Potential monomer or cross-linking agent for synthesizing novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in total synthesis and natural product analogue development.

Basic Information

Item	Detail
Product Name	8-Oxabicyclo[3.2.1]Oct-6-En-3-One,2-(1-Methylethyl)-,(1R,2S,5R)-Rel-(9Ci)
CAS No.	147729-86-0
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(1R,2S,5R)-rel-2-Isopropyl-8-oxabicyclo[3.2.1]oct-6-en-3-one; 2-Isopropyl-8-oxabicyclo[3.2.1]oct-6-en-3-one, (1R,2S,5R)-rel-; Bicyclic Lactone Derivative; Chiral Oxabicyclic Ketone; (rel)-(1R,2S,5R)-2-(Propan-2-yl)-8-oxabicyclo[3.2.1]oct-6-en-3-one
EINECS	Contact for details

Quality Control

Our 8-Oxabicyclo[3.2.1]Oct-6-En-3-One,2-(1-Methylethyl)-,(1R,2S,5R)-Rel-(9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ISO guidelines for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.