Description

5-o-Triphenylmethoxypentanol CAS NO 147726-64-5 is a specialized organic compound featuring a triphenylmethyl (trityl) protecting group attached to a pentanol chain via an ether linkage. This molecular architecture makes it a valuable intermediate in sophisticated organic synthesis, particularly for the protection of hydroxyl groups during multi-step reactions. It is primarily utilized by research and development chemists in the pharmaceutical and fine chemical industries who require high-purity building blocks for complex molecule assembly, such as active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Serves as a crucial building block for constructing advanced organic compounds in research and pilot-scale production.
• Hydroxyl Group Protection: The trityl group is used to selectively protect primary hydroxyl groups, enabling specific reactions elsewhere on the molecule.
• Oligonucleotide & Peptide Chemistry: Potential use in the synthesis of nucleosides, nucleotides, and peptides where temporary hydroxyl protection is required.
• Material Science Research: Employed in the development of novel polymers and dendrimers with specific functional group architectures.
• Academic & Industrial R&D: A reagent for methodological development and exploratory synthesis in chemistry laboratories worldwide.

Basic Information

Item	Detail
Product Name	5-o-Triphenylmethoxypentanol
CAS No.	147726-64-5
Molecular Formula	C24H26O2
Molecular Weight	346.47 g/mol
Synonyms	5-(Triphenylmethoxy)pentan-1-ol; 5-(Trityloxy)-1-pentanol; 1-Pentanol, 5-(triphenylmethoxy)-; 5-Hydroxypentyl triphenylmethyl ether; Trityl 5-hydroxypentyl ether; 5-O-Trityl-1-pentanol; 5-Trityloxypentanol; Pentanol, 5-(triphenylmethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 5-o-Triphenylmethoxypentanol is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and pharmaceutical intermediate applications. Comprehensive analytical testing, including HPLC, NMR, and GC, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.