Description

(-)-Ortho-Nicotine Diperchlorate CAS NO 147663-86-3 is a high-purity, specialized nicotine derivative salt, distinguished by its specific stereochemistry. This compound is of significant value in advanced research and development, particularly for its role as a key chiral intermediate or reference standard. It is primarily sought by professionals in the pharmaceutical, agrochemical, and life science sectors for applications requiring precise molecular configuration and high chemical purity.

Application

• Pharmaceutical Research: Serves as a critical chiral building block or intermediate in the synthesis of novel nicotinic receptor ligands and other bioactive molecules.
• Analytical Reference Standard: Used as a high-purity standard in chromatographic analysis (HPLC, GC) for method development, validation, and quality control of nicotine-related compounds.
• Biochemical Studies: Employed in neuroscience and pharmacology research to study the binding affinity and functional activity at neuronal nicotinic acetylcholine receptors (nAChRs).
• Agrochemical Development: Investigated as a potential precursor or analog in the development of new, selective insecticides and pest control agents.
• Chemical Synthesis: Acts as a versatile intermediate for the preparation of more complex, stereochemically defined nicotine derivatives for various industrial applications.

Basic Information

Item	Detail
Product Name	(-)-Ortho-Nicotine Diperchlorate
CAS No.	147663-86-3
Molecular Formula	C10H15Cl2N2O8
Molecular Weight	354.14 g/mol
Synonyms	(-)-2'-(Ortho)-Nicotine Diperchlorate; (S)-(-)-2'-Nicotine Diperchlorate; L-(-)-2'-Nicotine Diperchlorate; 1-Methyl-2-(2-pyridyl)pyrrolidine Diperchlorate; (2'S)-1-Methyl-2-(pyrid-2-yl)pyrrolidinium Diperchlorate; Nicotine-2'-diperchlorate; (-)-2'-C-Nicotine diperchlorate
EINECS	Contact for details

Quality Control

Our (-)-Ortho-Nicotine Diperchlorate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the perchlorate salt nature, store separately from combustible materials and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.