Description

(4-Pyrrolidin-1-Ylbut-2-Yn-1-Yl)Amine Dihydrochloride is a high-purity, specialized organic building block primarily used in advanced pharmaceutical research and development. This compound matters as a critical intermediate for synthesizing complex molecules, particularly in medicinal chemistry for creating potential drug candidates targeting neurological and other therapeutic areas. It is essential for research chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a building block for the pilot and commercial-scale production of specialized fine chemicals.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic research.
• Academic & Institutional Research: Employed in university and government labs for fundamental organic synthesis and chemical biology projects.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	(4-Pyrrolidin-1-Ylbut-2-Yn-1-Yl)Amine Dihydrochloride
CAS No.	147555-79-1
Molecular Formula	C10H19Cl2N2
Molecular Weight	238.18 g/mol
Synonyms	1-(4-Aminobut-2-yn-1-yl)pyrrolidine dihydrochloride; 4-(Pyrrolidin-1-yl)but-2-yn-1-amine dihydrochloride; 2-Butyn-1-amine, 4-(1-pyrrolidinyl)-, dihydrochloride; N-(2-Butynyl)pyrrolidine dihydrochloride; 4-(Pyrrolidin-1-yl)but-2-ynylamine dihydrochloride; 1-(4-Amino-2-butynyl)pyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our (4-Pyrrolidin-1-Ylbut-2-Yn-1-Yl)Amine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.