Description

7-Fluoro-2-Phenyl-4-Quinolone is a high-purity fluorinated quinolone derivative, serving as a critical advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. Its core value lies in enabling the synthesis of novel compounds with potential biological activity, particularly in the development of targeted therapeutic agents. This product is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate within the quinolone chemical space.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting bacterial infections, cancer, or central nervous system disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive molecules.
• Agrochemical Development: Serves as a precursor in the research and production of new-generation pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value fluorinated organic compounds.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme mechanisms or cellular pathways.
• Material Science Research: Investigated as a precursor for organic electronic materials or fluorescent markers due to the quinolone core structure.

Basic Information

Product Name	7-Fluoro-2-Phenyl-4-Quinolone
CAS No.	147197-81-7
Molecular Formula	C₁₅H₁₀FNO
Molecular Weight	239.25 g/mol
Synonyms	7-Fluoro-2-phenyl-4(1H)-quinolone; 7-Fluoro-2-phenyl-1H-quinolin-4-one; 2-Phenyl-7-fluoro-4-quinolone; 7-Fluoro-2-phenylquinolin-4(1H)-one; 4(1H)-Quinolinone, 7-fluoro-2-phenyl-; 7-Fluoro-2-phenyl-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2-Phenyl-4-Quinolone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maximize stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.