Description

Methyl 2-(Difluoromethyl)-5-(4,5-Dihydro-1,3-Thiazol-2-Yl)-4-(2-Methyl Propyl)-6-(Trifluoromethyl)Pyridine-3-Carboxylate is a high-value, multi-functional heterocyclic compound featuring a unique combination of difluoromethyl, trifluoromethyl, and thiazoline moieties. This complex structure makes it a critical advanced pharmaceutical intermediate for the synthesis of novel active ingredients, particularly in agrochemical and medicinal chemistry. It is primarily sought by R&D organizations and fine chemical manufacturers engaged in developing next-generation crop protection agents and therapeutic candidates.

Application

• Key Intermediate for Agrochemicals: Serves as a core building block in the synthesis of modern, high-performance insecticides and fungicides.
• Pharmaceutical Research Intermediate: Used in medicinal chemistry for the discovery and development of new drug candidates, leveraging its fluorinated pyridine scaffold.
• Ligand and Catalyst Precursor: The thiazoline moiety can be utilized to develop novel ligands for asymmetric catalysis in fine chemical synthesis.
• Material Science Research: Investigated for the development of specialty chemicals and functional materials due to its unique fluorine-containing structure.

Basic Information

Product Name	Methyl 2-(Difluoromethyl)-5-(4,5-Dihydro-1,3-Thiazol-2-Yl)-4-(2-Methyl Propyl)-6-(Trifluoromethyl)Pyridine-3-Carboxylate
CAS No.	147172-37-0
Molecular Formula	C16H17F5N2O2S
Molecular Weight	396.38 g/mol
Synonyms	Methyl 2-(difluoromethyl)-5-(4,5-dihydro-1,3-thiazol-2-yl)-4-isobutyl-6-(trifluoromethyl)nicotinate; 3-Pyridinecarboxylic acid, 2-(difluoromethyl)-5-(4,5-dihydro-2-thiazolyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-, methyl ester; 2-(Difluoromethyl)-5-(4,5-dihydrothiazol-2-yl)-4-isobutyl-6-(trifluoromethyl)nicotinic acid methyl ester; CAS 147172-37-0; Nicotinate derivative with thiazoline; Fluorinated pyridine-thiazoline intermediate
EINECS	Contact for details

Quality Control

Every batch of our Methyl 2-(Difluoromethyl)-5-(4,5-Dihydro-1,3-Thiazol-2-Yl)-4-(2-Methyl Propyl)-6-(Trifluoromethyl)Pyridine-3-Carboxylate is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.