Description

4-Amino-2-Methyl-8-(Trifluoromethyl)Quinoline is a high-value, multi-functional quinoline derivative distinguished by its amino and trifluoromethyl substituents. This compound serves as a critical advanced intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for research and development chemists and process engineers working on novel active ingredients, including kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies and kinase inhibitors.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the bioactivity of the quinoline scaffold.
• Material Science Precursor: Serves as a starting material for creating specialty chemicals, dyes, and functional materials.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for constructing complex heterocyclic compounds and exploring new catalytic reactions.
• Fluorinated Compound Library: An important component for building libraries of fluorinated compounds in drug discovery programs.

Basic Information

Product Name	4-Amino-2-Methyl-8-(Trifluoromethyl)Quinoline
CAS No.	147147-73-7
Molecular Formula	C11H9F3N2
Molecular Weight	226.20 g/mol
Synonyms	8-(Trifluoromethyl)-2-methylquinolin-4-amine; 2-Methyl-8-(trifluoromethyl)-4-quinolinamine; 4-Amino-2-methyl-8-trifluoromethylquinoline; 4-Quinolinamine, 2-methyl-8-(trifluoromethyl)-; 2-Methyl-8-(trifluoromethyl)quinolin-4-amine
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Methyl-8-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.