Description

4-Chloro-D-Phenylalanine Hydrochloride is a high-purity, non-natural amino acid derivative widely used in pharmaceutical research and development. This compound serves as a critical chiral building block and a key intermediate in the synthesis of more complex bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Biochemical Research: Used as a precursor or reference standard in enzymatic studies and metabolic pathway analysis.
• Peptide Synthesis: Employed as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry to introduce the 4-chloro-D-phenylalanine moiety.
• Proteomics & Labeling: Potential utility in the development of chemical probes and affinity labels for protein interaction studies.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in the preparation of enantiomerically pure compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in regulatory filings.

Basic Information

Product Name	4-Chloro-D-Phenylalanine Hydrochloride
CAS No.	147065-05-2
Molecular Formula	C9H11Cl2NO2
Molecular Weight	236.10 g/mol
Synonyms	(R)-2-Amino-3-(4-chlorophenyl)propanoic acid hydrochloride; D-4-Chlorophenylalanine HCl; (R)-4-Chlorophenylalanine hydrochloride; D-p-Chlorophenylalanine hydrochloride; (2R)-2-Amino-3-(4-chlorophenyl)propanoic acid hydrochloride; 4-Chloro-D-Phe-OH·HCl; 4-Cl-D-Phe·HCl
EINECS	Contact for details

Quality Control

Our 4-Chloro-D-Phenylalanine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification and impurity profiling. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.