Description

5-Bromoquinazolin-4-Ol is a versatile and high-value brominated quinazoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it an essential building block for constructing complex heterocyclic compounds, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents for oncology and inflammatory diseases.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or functional component in the development of advanced organic electronic materials and dyes.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs, structure-activity relationship (SAR) studies, and library synthesis in academic and CRO laboratories.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and biochemical tools for studying enzyme function and cellular pathways.

Basic Information

Product Name	5-Bromoquinazolin-4-Ol
CAS No.	147006-47-1
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	5-Bromo-4-hydroxyquinazoline; 4-Hydroxy-5-bromoquinazoline; 5-Bromoquinazolin-4-ol; 5-Bromo-4(3H)-quinazolinone; 5-Bromoquinazolin-4(3H)-one; 5-Bromo-4-quinazolinol; 147006-47-1
EINECS	Contact for details

Quality Control

Our 5-Bromoquinazolin-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by techniques including HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our clients' regulatory filing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.