Description

Methyl 2-Amino-3-(4-Cyanophenyl)Propanoate Hydrochloride is a high-purity, non-natural amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the combination of a protected amino acid ester functionality with a versatile nitrile group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in protease inhibitor and CNS-active molecule libraries.
• Peptidomimetics Synthesis: Used to incorporate non-natural amino acid residues into peptide analogs to enhance stability, bioavailability, and biological activity.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and plant growth regulators with specific chiral requirements.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and molecular tools for studying enzyme function and protein-protein interactions.
• Custom Synthesis Building Block: Provides a versatile handle for further chemical transformations (e.g., hydrolysis, reduction of the nitrile) in contract research and manufacturing.

Basic Information

Product Name	Methyl 2-Amino-3-(4-Cyanophenyl)Propanoate Hydrochloride
CAS No.	146693-08-5
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	Methyl 2-amino-3-(4-cyanophenyl)propanoate hydrochloride; Methyl (S)-2-amino-3-(4-cyanophenyl)propanoate hydrochloride (if applicable); 4-Cyanophenylalanine methyl ester hydrochloride; 2-Amino-3-(4-cyanophenyl)propionic acid methyl ester hydrochloride; L-4-Cyanophenylalanine methyl ester hydrochloride; (S)-2-Amino-3-(4-cyanophenyl)propanoic acid methyl ester hydrochloride; Methyl β-amino-p-cyanohydrocinnamate hydrochloride; p-Cyanophenylalanine methyl ester HCl
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-(4-Cyanophenyl)Propanoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.