Description

Cyclopropanecarboxylic Acid, 1-Amino-2-(Hydroxymethyl)-3-Phenyl- (9Ci) is a specialized chiral cyclopropane derivative that serves as a high-value synthetic intermediate. This compound is crucial for constructing complex molecular architectures due to its rigid cyclopropane ring and multiple functional handles for chemical modification. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the cyclopropane moiety.
• Chiral Ligand & Catalyst Precursor: Serves as a starting material for synthesizing enantiomerically pure ligands used in asymmetric catalysis.
• Advanced Material Research: Employed in the development of specialty polymers and liquid crystals where the rigid structure imparts desired physical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-(Hydroxymethyl)-3-Phenyl- (9Ci)
CAS No.	146400-26-2
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	1-Amino-2-(hydroxymethyl)-3-phenylcyclopropanecarboxylic acid; (1R,2S,3R)-1-Amino-2-(hydroxymethyl)-3-phenylcyclopropanecarboxylic acid (for specific enantiomer); 3-Phenyl-1-aminocyclopropane-2-carboxylic acid methanol; Cyclopropanecarboxylic acid, 1-amino-2-(hydroxymethyl)-3-phenyl-; 2-(Hydroxymethyl)-3-phenyl-1-aminocyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-(Hydroxymethyl)-3-Phenyl- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.