Description

(R)-5-(Oxiran-2-Ylmethoxy)Quinoline is a high-purity chiral building block featuring a quinoline scaffold linked to an epoxide moiety. This compound is of significant value in asymmetric synthesis and pharmaceutical research, serving as a key intermediate for constructing complex molecules with defined stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring precise chiral control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) disorders.
• Asymmetric Catalysis Research: Used as a ligand precursor or a test substrate in the development of new catalytic systems for enantioselective synthesis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study enzyme mechanisms and biological pathways due to its reactive epoxide group.
• Material Science: Potential monomer or cross-linking agent in the synthesis of advanced polymers with specific optical or electronic properties.
• Agrochemical Research: Serves as an intermediate in the discovery of new chiral active ingredients for crop protection.

Basic Information

Product Name	(R)-5-(Oxiran-2-Ylmethoxy)Quinoline
CAS No.	145679-40-9
Molecular Formula	C₁₄H₁₃NO₂
Molecular Weight	227.26 g/mol
Synonyms	(R)-5-((Oxiran-2-yl)methoxy)quinoline; (R)-5-(2,3-Epoxypropoxy)quinoline; (R)-Glycidyl 5-quinolyl ether; Quinoline, 5-[(2R)-2-oxiranylmethoxy]-; (R)-Epoxypropyl quinolin-5-yl ether; (R)-5-Quinolyl glycidyl ether; (R)-5-(2-Oxiranylmethoxy)quinoline
EINECS	Contact for details

Quality Control

Our (R)-5-(Oxiran-2-Ylmethoxy)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.