Description

Dl-Norleucine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester CAS NO 145618-64-0 is a protected amino acid derivative, specifically a Boc-protected norleucine methyl ester, serving as a crucial building block in organic synthesis. Its primary value lies in providing a versatile and reactive intermediate for the controlled construction of peptides and complex organic molecules, where the Boc group offers orthogonal protection. This compound is essential for researchers and manufacturers in pharmaceutical development, peptide chemistry, and academic research requiring high-purity synthetic precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate norleucine residues with orthogonal Boc protection.
• Biochemical Research: Serves as a precursor in metabolic studies, protein engineering, and the development of enzyme inhibitors.
• Organic Synthesis: A versatile reagent for constructing complex organic molecules, including non-natural amino acids and chiral auxiliaries.
• Agrochemical Development: Potential intermediate in the research and synthesis of specialized agricultural chemicals.
• Material Science: Can be utilized in the development of specialty polymers and biomaterials.

Basic Information

Item	Details
Product Name	Dl-Norleucine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester
CAS No.	145618-64-0
Molecular Formula	C12H23NO4
Molecular Weight	245.32 g/mol
Synonyms	Boc-Nle-OMe; N-Boc-DL-norleucine methyl ester; N-(tert-Butoxycarbonyl)-DL-norleucine methyl ester; Methyl N-(tert-butoxycarbonyl)-DL-norleucinate; DL-2-Aminohexanoic acid, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Boc-DL-Nle-OMe; tert-Butyloxycarbonyl-DL-norleucine methyl ester
EINECS	Contact for details

Quality Control

Our Dl-Norleucine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.