Description

H-D-Lys(Z)-Ome Hcl CAS NO 145586-17-0 is a protected derivative of the essential amino acid L-lysine, specifically engineered for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity, optically active building blocks to construct complex peptide chains with precise stereochemistry. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Nα-protected and side-chain protected amino acid derivative for the controlled assembly of peptide sequences.
• Pharmaceutical Intermediate: In the research and development of peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation: For the site-specific modification of proteins, antibodies, or other biomolecules, leveraging its protected ε-amino group for selective deprotection and coupling.
• Biochemical Research: As a standard or reagent in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.
• Antibiotic Synthesis: As a precursor in the synthesis of certain peptide antibiotics and antimicrobial agents.

Basic Information

Product Name	H-D-Lys(Z)-Ome Hcl
CAS No.	145586-17-0
Molecular Formula	C15H23ClN2O4
Molecular Weight	330.81 g/mol
Synonyms	H-D-Lys(Z)-OMe hydrochloride; D-Lysine, N2-[(benzyloxy)carbonyl]-, methyl ester, hydrochloride (1:1); Methyl N2-[(benzyloxy)carbonyl]-D-lysinate hydrochloride; Methyl (2R)-6-amino-2-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride; Z-D-Lys-OMe · HCl; (R)-Methyl 2-((((benzyloxy)carbonyl)amino)-6-aminohexanoate hydrochloride; Nα-Carbobenzoxy-D-lysine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-D-Lys(Z)-Ome Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and peptide synthesis. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.