Description

2(1H)-Quinolinone, 3-Acetyl-4-(Methylthio)-8-(Phenylsulfonyl)- is a specialized heterocyclic organic compound featuring a quinolinone core substituted with acetyl, methylthio, and phenylsulfonyl functional groups. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Organic Synthesis Building Block: Used in the construction of more complex heterocyclic compounds due to its reactive functional groups.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Material Science: Investigated for use in the synthesis of organic electronic materials and specialty polymers.

Basic Information

Product Name	2(1H)-Quinolinone, 3-Acetyl-4-(Methylthio)-8-(Phenylsulfonyl)-
CAS No.	145499-14-5
Molecular Formula	C18H15NO4S2
Molecular Weight	373.45 g/mol
Synonyms	3-Acetyl-4-(methylthio)-8-(phenylsulfonyl)quinolin-2(1H)-one; 8-(Benzenesulfonyl)-3-acetyl-4-(methylthio)-1,2-dihydro-2-quinolinone; 3-Acetyl-4-methylsulfanyl-8-phenylsulfonyl-1H-quinolin-2-one; 145499-14-5; 3-Acetyl-4-(methylthio)-8-(phenylsulfonyl)-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.