Description

2H-1-Benzazepin-2-One, 6-Fluoro-1,3,4,5-Tetrahydro- is a high-purity fluorinated benzazepinone derivative, a key advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its value lies in its precise molecular architecture, which is critical for developing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly those focused on central nervous system (CNS) and cardiovascular drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to introduce the fluorinated benzazepinone scaffold into target molecules.
• Medicinal Chemistry Research: A key reagent for structure-activity relationship (SAR) studies and the development of new pharmacophores.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high-purity, complex heterocyclic structures.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2H-1-Benzazepin-2-One, 6-Fluoro-1,3,4,5-Tetrahydro-
CAS No.	145485-58-1
Molecular Formula	C₁₀H₁₀FNO
Molecular Weight	179.19 g/mol
Synonyms	6-Fluoro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one; 6-Fluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one; 6-Fluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; 6-Fluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one; 6-Fluoro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one; 6-Fluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-2-one; 6-Fluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; 6-Fluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one.
EINECS	Contact for details

Quality Control

Our 2H-1-Benzazepin-2-One, 6-Fluoro-1,3,4,5-Tetrahydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.