Description

2-Azabicyclo[2.2.1]Heptane-6-Carboxylicacid,Methylester,(1S-Exo)-(9Ci) is a high-purity chiral bicyclic lactam derivative, serving as a critical advanced pharmaceutical intermediate (API). This compound matters for its role as a sophisticated building block in the synthesis of complex, biologically active molecules, enabling precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in developing new therapeutic agents, particularly in the areas of neurology and antiviral research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block for constructing complex molecules with defined stereochemistry in medicinal chemistry.
• Neurological Research: Potential precursor in the synthesis of compounds targeting neurological pathways and receptors.
• Antiviral Drug Development: Employed in the scaffold development for potential antiviral and protease inhibitor candidates.
• Catalyst and Ligand Synthesis: Serves as a precursor for creating novel chiral catalysts and ligands used in enantioselective reactions.
• Academic and R&D Laboratories: Utilized in fundamental organic chemistry research and method development for complex molecule assembly.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Heptane-6-Carboxylicacid,Methylester,(1S-Exo)-(9Ci)
CAS No.	145375-03-7
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	(1S,2R,4S)-2-Azabicyclo[2.2.1]heptane-6-carboxylic acid methyl ester; (1S-exo)-2-Azabicyclo[2.2.1]heptane-6-carboxylic acid, methyl ester; Methyl (1S,2R,4S)-2-azabicyclo[2.2.1]heptane-6-carboxylate; exo-2-Azabicyclo[2.2.1]heptane-6-carboxylic acid methyl ester (1S-); Bicyclic Lactam Ester; 2-Azanorbornane-6-carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.1]Heptane-6-Carboxylicacid,Methylester,(1S-Exo)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high-purity standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, assay, chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.