Description

2-Hydroxy-4,5-Methylenedioxyamphetamine is a substituted amphetamine derivative of significant interest in advanced chemical research and development. This compound matters for its role as a key synthetic intermediate and reference standard in the study of psychoactive substances and their metabolic pathways. It is primarily needed by pharmaceutical R&D laboratories, forensic science institutions, and specialized chemical manufacturers engaged in analytical method development and neurochemical research.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of novel therapeutic agents targeting the central nervous system.
• Forensic Analysis & Toxicology: Used as a certified reference material (CRM) for the accurate identification and quantification of substances in forensic investigations and toxicology screenings.
• Metabolic Pathway Studies: Employed in biochemical research to investigate the metabolism, pharmacokinetics, and pharmacodynamics of amphetamine-related compounds.
• Analytical Method Development: Essential for calibrating analytical instruments such as HPLC, GC-MS, and LC-MS/MS, ensuring method validation and regulatory compliance in testing laboratories.
• Neurochemical Research: Utilized in academic and institutional research to study receptor binding affinities and the structure-activity relationships (SAR) of phenethylamine derivatives.
• Chemical Synthesis: Acts as a specialized building block for the synthesis of more complex molecules in medicinal chemistry and organic synthesis projects.

Basic Information

Product Name	2-Hydroxy-4,5-Methylenedioxyamphetamine
CAS No.	145284-65-7
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	2-Hydroxy-4,5-methylenedioxyamphetamine; 2-Hydroxy-MDA; 2-OH-MDA; 4,5-Methylenedioxy-2-hydroxyamphetamine; 1-(1,3-Benzodioxol-5-yl)-2-aminopropan-2-ol; α-Methyl-4,5-methylenedioxyphenethylamine-2-ol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4,5-Methylenedioxyamphetamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.