Description

7,8-Difluoroquinoline is a high-purity, fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key precursor for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and physicochemical properties. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated quinolone and quinoline-based drug candidates, including potential antibiotics and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where fluorination enhances stability and efficacy.
• Material Science Research: Serves as a precursor for creating fluorinated organic semiconductors, ligands for catalysis, and other advanced functional materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel fluorination reactions and constructing complex heterocyclic frameworks.
• Ligand Synthesis: Useful for preparing specialized fluorinated ligands used in coordination chemistry and catalytic processes.

Basic Information

Product Name	7,8-Difluoroquinoline
CAS No.	145241-76-5
Molecular Formula	C9H5F2N
Molecular Weight	165.14 g/mol
Synonyms	7,8-Difluoroquinoline; Quinoline, 7,8-difluoro-; 7,8-Difluoro-quinoline; 145241-76-5; 7,8-Difluorochinolin; 7,8-二氟喹啉 (Chinese); 7,8-Difluoro-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our 7,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.