Description

Monosialylated, Galactosylated, Biantennary Glycan (A1) is a structurally defined, complex carbohydrate (oligosaccharide) with a specific branching pattern and terminal modifications. This high-purity glycan is a critical reference standard and building block for biopharmaceutical research and development. It is essential for scientists and manufacturers in the biotechnology and pharmaceutical industries who require precise glycan structures for analytical method development, glycoengineering, and the study of glycoprotein function and stability.

Application

• Biopharmaceutical Reference Standard: Used as a primary standard for the identification and quantification of glycans in therapeutic proteins (e.g., monoclonal antibodies, fusion proteins) via techniques like HPLC and LC-MS.
• Glycoengineering Research: Serves as a key substrate or target structure in studies aimed at controlling and optimizing the glycosylation profiles of recombinant proteins to enhance efficacy, stability, and safety.
• Diagnostic Reagent Development: Employed in the development of diagnostic assays and kits that detect or measure specific glycan-binding proteins (lectins) or antibodies related to disease states.
• Cell Biology & Glycobiology Studies: Utilized as a tool to investigate cell-surface interactions, signaling pathways, and the biological roles of specific glycan epitopes in health and disease.
• Enzyme Activity Assays: Acts as a specific substrate for characterizing the activity and specificity of glycosyltransferases, glycosidases, and other glycan-modifying enzymes.
• Quality Control (QC) in Biologics Manufacturing: Integral to the QC release testing of biotherapeutics to ensure batch-to-batch consistency and confirm the presence of critical quality attributes (CQAs) related to glycosylation.

Basic Information

Item	Detail
Product Name	Monosialylated, Galactosylated, Biantennary Glycan (A1)
CAS No.	145211-79-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	A1 Glycan; Biantennary N-Glycan A1; Monosialylated Biantennary Glycan; Sialylated Complex-type N-Glycan; NA2 (alternative naming); Disialylated Biantennary N-Glycan (related structure); Asialo, galactosylated, biantennary N-glycan (core structure); Glycan A1
EINECS	Contact for details

Quality Control

Our high-purity glycans are produced and tested under stringent quality systems. Each batch of Monosialylated, Galactosylated, Biantennary Glycan (A1) is subjected to comprehensive analytical characterization, including advanced chromatographic and mass spectrometric techniques, to confirm structural identity and purity. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure full traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area%)
Water Content (KF)	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.