Description

1,3-Dioxolane-4-Methanol,2-Methyl-2-(1-Methylethyl)-(9Ci) is a specialized heterocyclic compound with a protected diol functionality, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique structure, CAS NO 145194-86-1, is critical for introducing complex stereocenters and functional groups into target molecules with high precision. This chemical is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to construct active pharmaceutical ingredients (APIs), advanced materials, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its structural motifs contribute to biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent for synthesizing specialty polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.
• Material Science: Potential application in the development of novel organic electronic materials or liquid crystals.

Basic Information

Product Name	1,3-Dioxolane-4-Methanol,2-Methyl-2-(1-Methylethyl)-(9Ci)
CAS No.	145194-86-1
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	2-Methyl-2-isopropyl-1,3-dioxolane-4-methanol; 4-(Hydroxymethyl)-2-isopropyl-2-methyl-1,3-dioxolane; 2-Isopropyl-2-methyl-1,3-dioxolane-4-methanol; (4-Hydroxymethyl-2-isopropyl-2-methyl-1,3-dioxolane); 1,3-Dioxolane-4-methanol, 2-methyl-2-(1-methylethyl)-; Acetone Isopropylidene Glycerol Derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Methanol,2-Methyl-2-(1-Methylethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C/59-77°F). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.