Description

2-Azabicyclo[2.2.2]Octane-2,3-Dicarboxylic Acid, 2-(9H-Fluoren-9-Ylmethyl) Ester, (S)- (9Ci) is a high-value, optically pure bicyclic amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid, three-dimensional scaffold is essential for constructing complex molecular architectures with precise stereochemical control. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Peptidomimetic & Constrained Peptide Design: Its bicyclic structure is incorporated to induce specific conformational restraints in peptide analogs, enhancing stability and bioactivity.
• Agrochemical Research: Employed in the design and synthesis of novel, stereochemically defined herbicides and fungicides.
• Material Science: Potential monomer for creating specialty polymers with unique structural and chiral properties.
• Academic & Process Chemistry: Serves as a valuable reference standard and starting material for methodological development in synthetic organic chemistry.

Basic Information

Item	Details
Product Name	2-Azabicyclo[2.2.2]Octane-2,3-Dicarboxylic Acid, 2-(9H-Fluoren-9-Ylmethyl) Ester, (S)- (9Ci)
CAS No.	144976-83-0
Molecular Formula	C24H23NO4
Molecular Weight	389.45 g/mol
Synonyms	(S)-2-(9H-Fluoren-9-ylmethoxycarbonyl)-2-azabicyclo[2.2.2]octane-3-carboxylic Acid; Fmoc-(S)-Abo-OH; (S)-Fmoc-2-Aza-bicyclo[2.2.2]octane-3-carboxylic Acid; (S)-N-Fmoc-2-azabicyclo[2.2.2]octane-3-carboxylic Acid; (S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-azabicyclo[2.2.2]octane-3-carboxylic Acid; (3S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.2]octane-3-carboxylic Acid; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)bicyclo[2.2.2]octane-2,3-dicarboxylic acid 2-methyl ester
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.2]Octane-2,3-Dicarboxylic Acid, 2-(9H-Fluoren-9-Ylmethyl) Ester, (S)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.