Description

(1-Boc-7-Azaindol-3-Methyl)Trimethylammonium Iodide is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies for the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Organic Synthesis: Serves as a versatile reagent for introducing the protected 7-azaindole moiety into more complex molecular architectures.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new chemical entities (NCEs).
• Bioconjugation & Probe Synthesis: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	(1-Boc-7-Azaindol-3-Methyl)Trimethylammonium Iodide
CAS No.	144866-90-0
Molecular Formula	C₁₆H₂₄IN₃O₂
Molecular Weight	417.28 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-(trimethylammoniomethyl)-1H-pyrrolo[2,3-b]pyridine Iodide; 1-Boc-3-(trimethylaminomethyl)-7-azaindole Iodide; 1-Boc-7-aza-3-trimethylaminomethylindole Iodide; 1H-Pyrrolo[2,3-b]pyridine, 1-[(1,1-dimethylethoxy)carbonyl]-3-[(trimethylammonio)methyl]-, iodide (1:1); 7-Azaindole-3-methyltrimethylammonium Iodide, N1-Boc protected; tert-Butyl 3-(trimethylammoniomethyl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate Iodide
EINECS	Contact for details

Quality Control

Our (1-Boc-7-Azaindol-3-Methyl)Trimethylammonium Iodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.