Description

Reveromycin C CAS NO 144860-69-5 is a specialized polyketide antibiotic compound belonging to the reveromycin family, known for its unique biological activity. This compound is of significant interest in advanced life science research due to its specific inhibitory effects on eukaryotic cell growth, particularly targeting osteoclasts. It serves as a critical research-grade biochemical for pharmaceutical R&D, oncology studies, and investigations into bone metabolism disorders.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of novel therapeutics.
• Oncology and Cancer Biology Studies: Utilized in vitro to study its effects on cancer cell proliferation and apoptosis, given its specific cytotoxic properties.
• Bone Metabolism Research: Investigated for its potential role in treating osteoporosis and other bone-resorptive diseases due to its selective inhibition of osteoclast function.
• Biochemical Pathway Analysis: Serves as a precise molecular tool to probe and elucidate specific intracellular signaling pathways and protein interactions.
• Antifungal and Antimicrobial Studies: Used in microbiological research to explore its spectrum of activity against various fungal and bacterial strains.
• Academic and Institutional Research: A vital reagent for universities and research institutes conducting fundamental studies in chemical biology and medicinal chemistry.

Basic Information

Product Name	Reveromycin C
CAS No.	144860-69-5
Molecular Formula	C29H42O9
Molecular Weight	534.64 g/mol
Synonyms	Reveromycin C; Antibiotic 1485A; Antibiotic 1485-A; Reveromycin C (Antibiotic 1485A); Reveromycin C (1485A); (3S,4R,5S,6R,8R,10R,12R,13S,14E,16E,18E,20S,21R)-20,21-Dihydroxy-4,5,13-trimethyl-3-[(1E)-1-propen-1-yl]-9-oxo-8-(2-oxoethyl)-1-oxacyclooctadeca-14,16,18-triene-6,10,12-tricarboxylic acid
EINECS	Contact for details

Quality Control

Our Reveromycin C is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA), documenting identity, purity, and related substances, is provided with every shipment to support your compliance and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product at -20°C or below. The container should be kept in a cool, dry, and well-ventilated area. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.