Description

1H-Indene-2-Methanamine, 2-Amino-2,3-Dihydro- is a specialized amino-functionalized indene derivative, serving as a versatile and high-value building block in advanced organic synthesis. Its unique fused-ring structure with an amine group makes it a critical intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Ligand Synthesis: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or functionalizing agent for creating specialty polymers with enhanced thermal or mechanical properties.
• Agrochemical Research: Employed in the development of new pesticides and herbicides due to its bioactive scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as charge-transport layers or light-emitting components.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1H-Indene-2-Methanamine, 2-Amino-2,3-Dihydro-
CAS No.	144800-63-5
Molecular Formula	C10H11N
Molecular Weight	145.20 g/mol
Synonyms	2-Amino-2,3-dihydro-1H-indene-2-methanol; 2-(Aminomethyl)-2,3-dihydro-1H-inden-2-ol; 1H-Indene-2-methanamine, 2-amino-2,3-dihydro-; 2-Amino-2,3-dihydro-1H-indene-2-methanol; (2-Hydroxy-2,3-dihydro-1H-inden-2-yl)methanamine; 2,3-Dihydro-2-(hydroxymethyl)-1H-inden-2-amine; 2-(Aminomethyl)indan-2-ol
EINECS	Contact for details

Quality Control

Our 1H-Indene-2-Methanamine, 2-Amino-2,3-Dihydro- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as required)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.