Description

4-Chloro-3-Nitrobenzene-1,2-Diamine is a high-purity aromatic diamine derivative, serving as a critical advanced intermediate in organic synthesis. Its unique structure, featuring both chloro and nitro substituents on a benzene diamine backbone, makes it a versatile building block for creating complex heterocyclic systems and functional dyes. This compound is essential for research and development chemists and production specialists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds, such as benzimidazoles and quinoxalines, which are core structures in various active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its halogenated nitroaniline structure contributes to biological activity.
• Dye and Pigment Manufacturing: Serves as a crucial intermediate for producing azo dyes and other high-performance organic pigments, imparting color fastness and specific hue properties.
• Polymer and Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, including polyimides and epoxy resins, enhancing thermal and mechanical properties.
• Research & Development: Employed in academic and industrial R&D labs for method development and as a building block in combinatorial chemistry and drug discovery programs.
• Chemical Synthesis Reagent: Utilized in various organic transformations, including nucleophilic aromatic substitution and reduction reactions, to create more complex molecular architectures.

Basic Information

Product Name	4-Chloro-3-Nitrobenzene-1,2-Diamine
CAS No.	144729-44-2
Molecular Formula	C6H6ClN3O2
Molecular Weight	187.58 g/mol
Synonyms	1,2-Diamino-4-chloro-3-nitrobenzene; 4-Chloro-3-nitro-1,2-benzenediamine; 3-Nitro-4-chloro-o-phenylenediamine; 2-Amino-4-chloro-5-nitroaniline; 4-Chloro-3-nitro-o-phenylenediamine; o-Phenylenediamine, 4-chloro-3-nitro-; Benzene-1,2-diamine, 4-chloro-3-nitro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Nitrobenzene-1,2-Diamine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.