Description

4-Ethynylbenzoic Acid Sodium Salt is a versatile and reactive organic salt, serving as a crucial building block in advanced chemical synthesis. Its value lies in the unique combination of a benzoic acid moiety and a terminal alkyne group, which enables efficient coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via click chemistry (CuAAC) and Sonogashira cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require a rigid aromatic backbone with a reactive handle.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and metal-organic frameworks (MOFs) with tailored properties.
• Bioconjugation & Probe Synthesis: Facilitates the labeling of biomolecules (proteins, peptides, nucleic acids) with fluorescent dyes or other reporter groups for diagnostic and research applications.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysts used in fine chemical manufacturing.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and chemical biology.

Basic Information

Product Name	4-Ethynylbenzoic Acid Sodium Salt
CAS No.	144693-65-2
Molecular Formula	C9H5NaO2
Molecular Weight	168.12 g/mol
Synonyms	Sodium 4-Ethynylbenzoate; Benzoic acid, 4-ethynyl-, sodium salt (1:1); 4-Carboxyphenylacetylene Sodium Salt; p-Ethynylbenzoic Acid Sodium Salt; Sodium p-Ethynylbenzoate; (4-Ethynylphenyl)carboxylic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our 4-Ethynylbenzoic Acid Sodium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.