Description

Lubeluzole CAS NO 144665-07-6 is a high-purity pharmaceutical intermediate and research chemical of significant interest in neuroscience and medicinal chemistry. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents targeting neurological pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in developing treatments for central nervous system disorders. Our supply is characterized by stringent quality control to ensure consistency and reliability for critical research and development applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced drug candidates for neurological research.
• Neuroscience Research: Used as a reference standard or active compound in studies investigating neuroprotective mechanisms and stroke-related pathways.
• Medicinal Chemistry: Serves as a core scaffold for the design and development of new chemical entities targeting glutamate receptors and related systems.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening assays for drug discovery programs.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for preclinical investigation and pharmacological profiling.
• GMP Manufacturing Support: Available in grades suitable for supporting early-stage process development and non-GMP scale-up activities.

Basic Information

Product Name	Lubeluzole
CAS No.	144665-07-6
Molecular Formula	C17H16F3N3O2S
Molecular Weight	383.39 g/mol
Synonyms	Lubeluzole; (R)-Lubeluzole; BIIR-561 CL; R 72 163; Prophylin; 1H-Benzimidazole, 2-[[(1R)-2-(4-fluorophenyl)-1-methylethyl]amino]-4-(trifluoromethyl)-; 2-[[(1R)-2-(4-Fluorophenyl)-1-methylethyl]amino]-4-(trifluoromethyl)-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our Lubeluzole is manufactured under strict quality management systems to ensure it meets the exacting standards required for research and development. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with relevant guidelines for research chemicals and can provide material suitable for various stages of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.