Description

Ethanone, 1-(3-Hydroxybicyclo[2.2.1]Hept-1-Yl)-, Exo- (9Ci) is a specialized bicyclic ketone derivative with a defined stereochemistry, serving as a valuable chiral building block in advanced organic synthesis. This compound is critical for the development of complex molecular architectures due to its rigid, functionalized norbornane skeleton. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its stereochemistry for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in enantioselective catalytic reactions.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, particularly in cycloaddition and functionalization reactions.
• Material Science: Potential monomer or cross-linking agent for the synthesis of polymers with unique thermal and mechanical properties.

Basic Information

Product Name	Ethanone, 1-(3-Hydroxybicyclo[2.2.1]Hept-1-Yl)-, Exo- (9Ci)
CAS No.	144657-41-0
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	exo-1-(3-Hydroxybicyclo[2.2.1]hept-1-yl)ethanone; exo-3-Hydroxy-1-acetylnorbornane; 1-Acetyl-3-hydroxybicyclo[2.2.1]heptane, exo-; 3-Hydroxy-1-acetylnorbornane (exo-); 1-(exo-3-Hydroxybicyclo[2.2.1]hept-1-yl)ethan-1-one; Bicyclo[2.2.1]heptane-1-acetyl-3-ol, exo-; (1R,2S,3R,4S)-3-Hydroxybicyclo[2.2.1]heptan-2-yl methyl ketone (relative stereochemistry)
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3-Hydroxybicyclo[2.2.1]Hept-1-Yl)-, Exo- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (exo- isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.