Description

(S)-[(3,4-Difluorophenoxy)Methyl]-Oxirane is a high-purity chiral epoxide building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in the fine chemical, agrochemical, and pharmaceutical industries who require enantiomerically pure intermediates for the development of active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for creating chiral dopants and other specialty chemicals used in electronic displays and optical materials.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in the development and testing of new asymmetric catalytic processes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring high stereochemical fidelity and purity.

Basic Information

Product Name	(S)-[(3,4-Difluorophenoxy)Methyl]-Oxirane
CAS No.	144574-27-6
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	(S)-Glycidyl 3,4-Difluorophenyl Ether; (S)-2-[(3,4-Difluorophenoxy)methyl]oxirane; (S)-Epichlorohydrin 3,4-Difluorophenyl Ether Derivative; (S)-1,2-Epoxy-3-(3,4-difluorophenoxy)propane; (S)-3,4-Difluorophenyl Glycidyl Ether; (S)-(-)-[(3,4-Difluorophenoxy)Methyl]Oxirane; (S)-α,β-Epoxypropyl 3,4-Difluorophenyl Ether
EINECS	Contact for details

Quality Control

Our (S)-[(3,4-Difluorophenoxy)Methyl]-Oxirane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.