Description

2-Cyclohexyl-Malonic Acid Monoethyl Ester is a versatile malonic acid derivative ester, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in its ability to introduce the cyclohexyl moiety and a functionalized malonate group, enabling the construction of complex molecular architectures with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and cardiovascular diseases.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators with specific stereochemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials.
• Asymmetric Synthesis: Employed in catalytic asymmetric reactions to produce enantiomerically pure compounds for high-value applications.
• Polymer Chemistry: Monomer or modifier for synthesizing specialized polymers with tailored thermal and mechanical properties.
• Research & Development: Critical reagent in academic and industrial R&D for methodological studies and novel compound library generation.

Basic Information

Product Name	2-Cyclohexyl-Malonic Acid Monoethyl Ester
CAS No.	144569-86-8
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	Monoethyl 2-Cyclohexylmalonate; Ethyl Hydrogen 2-Cyclohexylmalonate; 2-Cyclohexylpropanedioic Acid Monoethyl Ester; Ethyl 2-Cyclohexylmalonate Hydrogen; 1-Ethoxy-1-oxo-2-cyclohexylpropan-2-oic Acid; 2-Cyclohexylmalonic Acid Ethyl Ester; Monoethyl Cyclohexylmalonate; Cyclohexylmalonic Acid Monoethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Cyclohexyl-Malonic Acid Monoethyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for synthetic applications. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, purity, and impurity profiles. Our commitment to cGMP principles and regulatory compliance (REACH, FDA DMF where applicable) ensures consistent quality and supply chain reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.