Description

Udp-n-Acetylmuramyl-Ala-Glu-Lys-Ala-Lactate CAS NO 144483-60-3 is a specialized, high-purity biochemical intermediate, specifically a synthetic muramyl peptide derivative. This compound is critical for research and development in immunology and vaccine adjuvants, serving as a key building block for studying peptidoglycan biosynthesis and innate immune system activation. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on novel immunotherapies and antibacterial strategies.

Application

• Immunological Research: As a defined synthetic substrate for studying the enzymatic pathways of bacterial cell wall (peptidoglycan) biosynthesis.
• Vaccine Adjuvant Development: Investigation of muramyl peptide derivatives as potential immunomodulators and adjuvants to enhance vaccine efficacy.
• Enzyme Assay Substrate: Used in biochemical assays to study the activity and inhibition of key enzymes like Mur ligases involved in bacterial cell wall formation.
• Toll-like Receptor (TLR) Research: Serves as a research tool for probing TLR2 and NOD2 receptor signaling pathways in innate immunity.
• Pharmaceutical Intermediate: Acts as a high-value synthetic precursor in the development of novel antibacterial agents or immunostimulants.
• Biochemical Standard: Provides a pure reference standard for analytical method development and quality control in related biopharmaceutical processes.

Basic Information

Product Name	Udp-n-Acetylmuramyl-Ala-Glu-Lys-Ala-Lactate
CAS No.	144483-60-3
Molecular Formula	C41H63N7O26P2
Molecular Weight	1155.93 g/mol
Synonyms	UDP-MurNAc-pentapeptide(D-lactate); UDP-N-Acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-lactate; UDP-MurNAc-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Lac; Uridine diphosphate N-acetylmuramyl pentapeptide (D-lactate); Park's Nucleotide (D-Lactate variant); UDP-MurNAc-pentapeptide (D-Lac); Bacterial cell wall precursor UDP-MurNAc-pentadepsipeptide
EINECS	Contact for details

Quality Control

Our Udp-n-Acetylmuramyl-Ala-Glu-Lys-Ala-Lactate is manufactured under controlled conditions to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to stringent in-house quality protocols, and specifications can be aligned with customer-specific requirements for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.