Description

n-(3-Hydroxybutanoyl)Homoserine Lactone is a high-purity, synthetic quorum sensing molecule belonging to the class of acyl-homoserine lactones (AHLs). This compound serves as a critical signaling molecule for studying and manipulating bacterial communication pathways, particularly in Gram-negative bacteria. It is essential for researchers and developers in the fields of microbiology, anti-infective drug discovery, and agricultural biotechnology who require reliable, well-characterized biochemical tools.

Application

• Microbiological Research: Used as a standard or agonist in quorum sensing studies to investigate bacterial virulence, biofilm formation, and bioluminescence.
• Drug Discovery & Development: Serves as a key intermediate or target molecule in screening for novel quorum sensing inhibitors (QSIs) and anti-virulence agents.
• Agricultural Biotechnology: Applied in research to disrupt pathogenic bacterial communication in crops, exploring alternative strategies to traditional antibiotics.
• Industrial Fermentation: Utilized in controlled studies to understand and potentially engineer microbial consortia for improved metabolite production.
• Academic & Institutional Labs: A fundamental reagent for graduate-level and post-doctoral research in molecular microbiology and synthetic biology.
• Diagnostic Development: Can be used in the development of biosensors and assays designed to detect specific bacterial quorum sensing activity.

Basic Information

Product Name	n-(3-Hydroxybutanoyl)Homoserine Lactone
CAS No.	126049-72-7
Molecular Formula	C10H15NO5
Molecular Weight	229.23 g/mol
Synonyms	3-Hydroxybutanoyl Homoserine Lactone; N-(3-Hydroxybutyryl)-L-homoserine Lactone; C4-3-OH-HSL; 3-Oxo-C4-HSL (reduced form); N-[(3S)-3-Hydroxybutanoyl]-L-homoserine Lactone; BHL; N-(3-Hydroxybutanoyl)-HSL; AHL Signal Molecule
EINECS	Contact for details

Quality Control

Every batch of our n-(3-Hydroxybutanoyl)Homoserine Lactone is manufactured and analyzed under strict quality management protocols. We guarantee high chemical purity and structural integrity, supported by comprehensive analytical data including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the product label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.