Description

2,4-Dibromo-1,5-Difluoro-3-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique substitution pattern, which makes it a critical intermediate in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the dibromo-difluoro-nitrobenzene structure imparts specific biological activity.
• Material Science Research: Serves as a precursor for the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination due to the presence of bromine substituents.
• Nucleophilic Aromatic Substitution: The nitro and fluorine groups activate the ring for substitution, useful for introducing diverse functional groups.
• Dye and Pigment Intermediate: Employed in the synthesis of complex halogenated dyes and organic pigments.

Basic Information

Product Name	2,4-Dibromo-1,5-Difluoro-3-Nitrobenzene
CAS No.	144450-58-8
Molecular Formula	C6HBr2F2NO2
Molecular Weight	315.88 g/mol
Synonyms	1,5-Difluoro-2,4-dibromo-3-nitrobenzene; 3-Nitro-1,5-difluoro-2,4-dibromobenzene; Benzene, 2,4-dibromo-1,5-difluoro-3-nitro-; 2,4-Dibromo-1,5-difluor-3-nitrobenzol (German); 2,4-ジブロモ-1,5-ジフルオロ-3-ニトロベンゼン (Japanese)
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dibromo-1,5-Difluoro-3-Nitrobenzene is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. Our standard grade meets high-purity requirements for research and development. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.