Description

(S)-2-(2-Naphthyl)Glycolic Acid is a high-value chiral building block and intermediate of significant importance in asymmetric synthesis. Its enantiopure structure makes it a critical component for the development of optically active pharmaceuticals and advanced materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis, enabling stereoselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profile.
• Material Science Research: Employed in the synthesis of chiral monomers for advanced polymers and liquid crystals with specific optical properties.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization in fine chemical production.

Basic Information

Product Name	(S)-2-(2-Naphthyl)Glycolic Acid
CAS No.	144371-23-3
Molecular Formula	C₁₂H₁₀O₃
Molecular Weight	202.21 g/mol
Synonyms	(S)-2-Naphthylglycolic Acid; (S)-2-Hydroxy-2-(naphthalen-2-yl)acetic Acid; (S)-α-Hydroxy-2-naphthaleneacetic Acid; (S)-2-Naphthylhydroxyacetic Acid; L-2-Naphthylglycolic Acid; (S)-2-NGOH; (S)-Naphth-2-yl-glycolic Acid
EINECS	Contact for details

Quality Control

Our (S)-2-(2-Naphthyl)Glycolic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.