Description

Quinoline, 5-Fluoro-4-Methyl- (9Ci) is a specialized fluorinated quinoline derivative, a high-value building block in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials, where the introduction of fluorine atoms can dramatically alter biological activity and physicochemical properties. It is primarily utilized in pharmaceutical R&D, agrochemical discovery, and as a precursor for complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, antimicrobial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the fluorine moiety enhances bioactivity and environmental stability.
• Material Science Precursor: Serves as a building block for creating functional organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probe: Employed in the design of molecular probes and inhibitors to study enzyme function and biological pathways.
• Catalyst Ligand Synthesis: Utilized in the preparation of novel ligands for transition metal catalysis in asymmetric synthesis.
• Academic & Industrial R&D: Essential for methodological development and exploration of new fluorination chemistry and heterocyclic compound libraries.

Basic Information

Product Name	Quinoline, 5-Fluoro-4-Methyl- (9Ci)
CAS No.	144147-04-6
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	5-Fluoro-4-methylquinoline; 4-Methyl-5-fluoroquinoline; 5-Fluoro-4-methyl-quinoline; Quinoline, 5-fluoro-4-methyl-; 144147-04-6; 5-Fluoro-4-methyl-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our Quinoline, 5-Fluoro-4-Methyl- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of this high-purity intermediate for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong alkalis and fluorides. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.